https://mostowylab.com/news daily 0.75 2022-07-26 https://mostowylab.com/news/mgg-attends-viruses-of-microbes-in-portugal monthly 0.5 2022-07-26 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/7dd58f13-5d92-4d5a-ae2d-c4ef1acbf6b3/IMG_1060-red.jpg News/Blog - MGG attends Viruses of Microbes in Portugal - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://mostowylab.com/news/joint-embo-meeting-with-karnkowska-lab-and-dunin-horkawicz-lab-in-chciny monthly 0.5 2022-07-26 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/3a65bd81-e5f5-4e23-b7cb-8053517a5395/IMG_1030.jpg News/Blog - Joint EMBO meeting with Karnkowska Lab and Dunin-Horkawicz Lab in Chęciny - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://mostowylab.com/news/successful-msc-defence-by-jan-havrnek monthly 0.5 2021-07-22 https://mostowylab.com/news/jak-w-polsce-idzie-nam-zaszczepianie-populacji monthly 0.5 2021-05-03 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1619984387062-VSM0JWIC6ZXDLW21MV5A/Screenshot+2021-05-02+at+13.15.53.png News/Blog - (Polish) Jak w Polsce idzie nam zaszczepianie populacji? Źródło: Raport szczepień przeciwko COVID-19, ściągnięte 2.05.2021 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1619986172063-K4AISSIZ1BTLVJD57UW5/plot-first.png News/Blog - (Polish) Jak w Polsce idzie nam zaszczepianie populacji? https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1619986246950-4I3LMVJN2L887A5FGUOX/plot-full.png News/Blog - (Polish) Jak w Polsce idzie nam zaszczepianie populacji? https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1619987089999-0TDUZIYNFS4JOW5LB2XJ/plot-vaccines.png News/Blog - (Polish) Jak w Polsce idzie nam zaszczepianie populacji? https://mostowylab.com/news/we-are-recruiting monthly 0.5 2021-03-01 https://mostowylab.com/news/ncn-sonata-bis-grant-for-microbial-genomics-group monthly 0.5 2021-02-15 https://mostowylab.com/news/rafal-in-embo-encounters monthly 0.5 2021-02-03 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1612385409413-6D7AL2YY8CZLRM57YU1G/IMG_9609.jpg News/Blog - Rafal in EMBO Encounters https://mostowylab.com/news/jak-zaczynaj-i-kocz-si-pandemie monthly 0.5 2021-02-03 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1612383116556-KXT1UDX9HA3LUTSQWX6G/odpornosc-stadna.png News/Blog - (Polish) Jak zaczynają i kończą się pandemie? Epidemia przestaje rozwijać się wtedy, kiedy drogi zakaźne zostają zablokowane, a konkretnie proporcja (1-1/R0) z nich. Po lewej ilustracja sytuacji dla współczynnika bazowej reprodukcji R0=2 (zakażona osoba zaraża dwie kolejne), kiedy wszystkie drogi zakaźne są otwarte i epidemia się rozwija. Po prawej ponad 50% proc. z dróg zakaźnych zostało zablokowanych i epidemia zanika. Drogi zakaźne można zablokować na trzy sposoby. Pierwszym sposobem jest sztuczne ograniczenie kontaktów socjalnych, ale po przywróceniu ich epidemia nabiera na sile, ponieważ nie został osiągnięty poziom odporności zbiorowiskowej. Drugim sposobem jest naturalne wytworzenie takiej odporności przez swobodne rozprzestrzenianie się infekcji, ale w praktyce może to być trudne i – w przypadku groźnej choroby – niepotrzebnie narazić zdrowie i życie wielu ludzi. Trzecim i najlepszym sposobem jest sztuczne wytworzenie odporności zbiorowiskowej przez szczepionkę, ale implementacja dużej ilości szczepień jest wielkim wyzwaniem logistycznym. https://mostowylab.com/news/ncn-opus-grant-for-microbial-genomics-group monthly 0.5 2021-02-03 https://mostowylab.com/news/new-student-dana-pikulska-to-join-the-group monthly 0.5 2021-02-03 https://mostowylab.com/news/bacterial-hgt-rate monthly 0.5 2020-05-25 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1590317654308-R1C1H7I2QJBFH8KGZMVD/reproduction.png News/Blog - Evolutionary Purpose of bacterial Sex Two genetic strategies of reproduction: asexual and sexual. Which one is evolutionary better? In reality, the choice is not binary – in biology there is a whole spectrum of strategies between these two. https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1590317301255-YD4X0YAILUMA7U38FPPH/bacteria_htg_eng.png News/Blog - Evolutionary Purpose of bacterial Sex Drawing by Dorota Pacześniak https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1590399249801-2RJL28OE0G4QCR6ELFZF/hypotheses.png News/Blog - Evolutionary Purpose of bacterial Sex Does HGT rate influence evolutionary outcomes? If effective population sizes are small, HGT facilitates access to genetic diversity available in the population and lineages which undergo HGT more frequently will be more successful (“Genetics as limiting factor”). Conversely, if effective population sizes are large, HGT is not crucial for rapid access to genetic diversity and evolutionary success is primarily an outcome of selection (“Everything is everywhere”). In the former case what is shown in the green square is important; in the latter case it is not. https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1590398858080-8VFXIPUH026MO4J9RNEQ/resrec-eng.png News/Blog - Evolutionary Purpose of bacterial Sex https://mostowylab.com/news/why-are-bacterial-capsules-so-diverse monthly 0.5 2019-05-19 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558290684236-O7A0TPCIL3IHC27EQO0B/image-asset.png News/Blog - Why are bacterial capsules so diverse? https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558290722565-H5ME0IJEZA1V4MPK3EVS/image-asset.png News/Blog - Why are bacterial capsules so diverse? https://mostowylab.com/news/pneumococcal-capsule-evolution-on-steroids monthly 0.5 2019-05-19 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558289788654-5OJPPWN97NRR9O0HDXIX/screen-shot-2017-06-30-at-15-54-45.png News/Blog - Pneumococcal capsule: evolution on steroids Pneumococcal capsule. (From [2].) https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558289812267-0XRKL0EVOZFN9DPQ45YY/zcm0031525150001.jpg News/Blog - Pneumococcal capsule: evolution on steroids Polysaccharide capsule synthesis locus, cps. (From [3].) https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558290036223-5BP9SDOHLGARZFAAL0R8/image-asset.png News/Blog - Pneumococcal capsule: evolution on steroids Diversity of cps. (From [1].) https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558290134190-NP3NL4VYWJNHP6RCVML9/image-asset.png News/Blog - Pneumococcal capsule: evolution on steroids Summary of evolutionary history of serogroup 6 (A), serogroup 14/15 (B), serogroup 19 (C) and serogroup 23 (D). (From [1].) https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558290189225-SKH06Q0ZSBLHDS9CSMAB/screen-shot-2017-06-30-at-17-20-19.png News/Blog - Pneumococcal capsule: evolution on steroids Recombination highway map. (From [1].) https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558290244254-EF377H4O62QVITHR3C8D/image-asset.png News/Blog - Pneumococcal capsule: evolution on steroids Comparison of the molecular clock rate in three pneumococcal lineages: PMEN1, PMEN2 and PMEN14. (From [1].) https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558290283366-3O4G0D0GS81D24KUU8FG/5_selection2.png News/Blog - Pneumococcal capsule: evolution on steroids Diversifying selection acting on the wzd/wze genes in the cps. Distributions show the range of dN/dS values in the genome. (From [1].) https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558290337968-53O7QE7SOA4V6EYKH3H9/6_recombination2.png News/Blog - Pneumococcal capsule: evolution on steroids https://mostowylab.com/news/fastgear monthly 0.5 2019-05-19 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558288296780-DJDD8JO0W2KVGT9Z6KP2/fig1_example.png News/Blog - fastGEAR: detecting mosaicism in bacterial genomes https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558288593832-ZBVNCN2IOY67AJI5XMU5/hmm11.png News/Blog - fastGEAR: detecting mosaicism in bacterial genomes https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558288675806-B9YAI1KGRHM7DUY1SUG9/image-asset.png News/Blog - fastGEAR: detecting mosaicism in bacterial genomes https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558288710077-OGVCQGRO6OIJ5256UEXX/external.png News/Blog - fastGEAR: detecting mosaicism in bacterial genomes https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558288730679-HRZY9K2TEWMEE4LDS0OF/mlst.png News/Blog - fastGEAR: detecting mosaicism in bacterial genomes https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558288746416-L1ZH8GX6KZ4K0G35BM1W/image-asset.png News/Blog - fastGEAR: detecting mosaicism in bacterial genomes https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558288761102-133LDZQFHFI0QO5WYMMU/pbps.png News/Blog - fastGEAR: detecting mosaicism in bacterial genomes https://mostowylab.com/home daily 1.0 2022-07-26 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/94bddb48-66bc-45f8-8d42-537e319934fa/group-photo.png Home https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558536012179-NIC93FE82Q3NAHPGKCVN/main-coevol.png Home Bacterial surface sugars are highly diverse, and their diversity has likely emerged in the process of interaction with other factors, including antibodies and phages. To design long-lasting medical interventions against antibiotic resistant bacteria that target these sugars and are antibody- or phage-based, we need to first understand and quantify the selective regimes in which diversification (adaptation) can occur. See Mostowy & Holt (2018). https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1612382813463-6WQOSEKLRWV5GZRW3VSY/logo-poziom-en.png Home https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578413343042-HASTA2FGMG19U5X962IY/logo-eng-v2-artboards.png Home https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578392524328-ZFQPXIEHK51E6HJ0SHC4/asm_jed_ang.png Home https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578392724080-4OON64RM5LTZKZ3P1AWE/EMBO_logo_tagline_RGBblack_outlined.gif Home https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578413689140-PQRYLYZV4IX49RWJSAT9/IMP_ML_1CS_4CP_CLEAR-SPACE.png Home https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578413702750-4AC1DH89NQC9IOHBNQYL/SNF_RGB_E_POS.png Home https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578413713671-4QAEHZXSBMUIF68EYZ29/logo-actions-marie-curie.png Home https://mostowylab.com/research daily 0.75 2020-01-07 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558340296294-50KXEVOYM6MDTVIJW7R7/capsule-evolution.png Research https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558340990942-9KB6HIHQXDQE8CMIZ7FN/phage-interactions.png Research https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558341631055-TJJC7F06LDTSPU49I3U0/sex-bacteria Research https://mostowylab.com/publications daily 0.75 2023-01-17 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/d2d73f55-ad56-42bd-be74-89e63c31f00c/Screenshot+2023-01-17+at+07.12.27.png Publications - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578394280521-YNJFX2M9O8SH6BRDTOKV/lehtinen-et-al.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578394736980-RO9Y9JSUVC2G8J6JAY85/holt-et-al.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578394727740-1X1GDHQF6EENY1NHFBM6/torraca-et-al.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558296908977-SCBVNZZFG2ADTOO93LG3/image-asset.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558296984387-7BRX1RJBCCEHSDRUG8MF/Screenshot+2019-05-19+at+22.12.46.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558296891599-Q47J09LNIDO3GDZLIJFF/Screenshot+2019-05-19+at+22.11.47.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558297002701-X99WDC683QM8H6XR1PB9/Screenshot+2019-05-19+at+22.12.19.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558296871497-9MRPJ0B0PINKUK198HFT/image-asset.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558296933035-IR6FQP7TRFSLY0U5OS1L/Screenshot+2019-05-19+at+22.13.25.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558296447873-TRRIH2L43SV4LOTNTTTF/image-asset.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558296434184-X4XPSCMLNJFHR57XSWON/5_response1.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558296418624-QWKEK3UX15KSBY99A767/image-asset.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558296306377-TMB17ER59GWYOA7EHN6H/image-asset.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558295823912-WW4IZERJI653V1IWQOEE/image-asset.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558295613956-YT5QZKTTOKLUUJO4G7XO/2_gge1.png Publications https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558295178257-64EH5AAQ0Y0ENJ5HBJFV/image-asset.png Publications https://mostowylab.com/collaborators daily 0.75 2019-05-21 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558343267800-65JABUK9XW57B1D1VJQY/retreat_long_strip.png Collaborators https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558343276945-0E0ZUA0S3Q3YXHRCLHWM/mark-enright-and-dr-javid-resized-for-web.jpg Collaborators https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558441998218-O5DPPKEVCZQS79HR7E6T/2019-05-16_2.jpg Collaborators https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558344217341-PM1KSF0ZKTLG457AEDI9/aaron_darling1.jpg Collaborators https://mostowylab.com/opportunities daily 0.75 2023-02-27 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578413013253-ZXIUUS4Y7ZSX02KDAU2O/logo-eng-v2.png Opportunities https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1578412995147-YYY5A23PO8RGD7UUOV9O/EMBO_logo_tagline_RGBblack_outlined.gif Opportunities https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558346809677-O7UEF3AYS3Z0PUO6WG99/logo-actions-marie-curie.png Opportunities https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558346826430-BZEX5RL2CEBKWKONJZXL/074456-ncn.png Opportunities https://mostowylab.com/institute daily 0.75 2019-05-20 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558294115662-ZJ62ZK909SU1Z7YJLQ72/mct-1.jpg Institute https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1558294133217-9001XVAW4LAMFK0XAMWY/mct-4.jpg Institute https://mostowylab.com/contact-1 daily 0.75 2019-05-19 https://mostowylab.com/team daily 0.75 2022-07-26 https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/1613679896301-JOGTDZQ4FQAGVY1R3QGQ/MI3A2925-cropped.jpg Team https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/e9570bad-2291-40b0-a936-b554eb95413e/final.jpg Team https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/a5f466be-d8b9-4ab0-b7cb-7e599f159358/final.jpg Team https://images.squarespace-cdn.com/content/v1/5ce139641ecba2000171c9cd/9ea68287-ac0d-4339-90a2-50363c72060d/final.jpg Team - 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